PDMS deviceHere’s a tutorial from Corsolutions, a company based in Ithaca, New York that is utilized by academic, biotechnology, pharmaceutical and government researchers in seeking to enhance their microfluidic workflows, that discusses the process in fabricating a microfluidic device from PDMS. PDMS refers to polydimethylsiloxane, a silicon-based organic polymer that is widely used for microfluidic devices because it is easy to work with, biocompatible, economical and transparent down to 280 nanometer.

  1. First, mix the PDMS two-part kit, which is composed of the base and the cross-linking agent;
  2. Next, pour the liquid pre-polymer over a previously fabricated master mold.
  3. Cure the PDMS in an oven at 65°C for 24 hours.
  4. Peel the PDMS device from the master mold and cut as desired.
  5. Next the inlet and outlet ports on the device need to be fabricated.
  6. Fnally to interface the PDMS microdevice with fluid delivery pumps and detectors, CorSolutions compression connectors can be quickly and non-permanently placed over the inlet and outlet ports to make leak-tight connections.

For a much comprehensive detail of this tutorial, you can visit the original source from CorSolutions official website at http://www.mycorsolutions.com/pdms-tutorial.html.